Computationally Guided Stereocontrol of the Combined CH Functionalization/Cope Rearrangement

Computationally-guided Design of Cell Culture Bioreactors

Enzyme stabilization via computationally guided protein stapling.

Thermostabilization represents a critical and often obligatory step toward enhancing the robustness of enzymes for organic synthesis and other applications. While directed evolution methods have provided valuable tools for this purpose, these protocols are laborious and time-consuming and typically require the accumulation of several mutations, potentially at the expense of catalytic function. ...

Ch-ch-ch-ch-Changes

Change is not made without inconvenience, even from worse to better. Richard Hooker, as quoted in the preface of Samuel Johnson's A Dictionary of the English Language Oh, so they have internet on computers now! Homer Simpson It is with great pleasure that I announce the rebirth of the former print journal of the Canadian Geriatrics Society as a new online publication, the Canadian Geriatrics Jo...

Stereocontrol in Radical Polymerization of Acrylamides with Combined Lewis Acids of AlCl3-FeCl2

Mirror neurons and imitation: A computationally guided review

Neurophysiology reveals the properties of individual mirror neurons in the macaque while brain imaging reveals the presence of 'mirror systems' (not individual neurons) in the human. Current conceptual models attribute high level functions such as action understanding, imitation, and language to mirror neurons. However, only the first of these three functions is well-developed in monkeys. We th...